hypodermis

Lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. The hypodermis is used mainly for fat storage[WP]. Every claim on this page comes from the Leumas anatomy graph and carries its source.

What the hypodermis is

Lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. The hypodermis is used mainly for fat storage[WP]. The atlas records it as a tissue at the tissue scale in the human body.

Where the hypodermis is

It sits within the integumentary system. Only the system is known. The position shown carries almost no spatial information.

What the hypodermis connects to

The atlas records 15 typed relationships for it, across 6 kinds of connection. part of integument and integumental system.

Supply and innervation

This dataset asserts no arterial supply, venous drainage or innervation for the hypodermis. Only a minority of structures carry those edges here, so an empty answer means nothing has been recorded — not that there is nothing to record.

Also called

Also recorded as hypoderm, vertebrate hypodermis, sub-tegumental tissue, subcutaneous tissue, subcutis and subtegumental tissue, and 2 more. Searching any of those names reaches this page.

Source

Uberon multi-species anatomy ontology (Mungall et al.), CC BY 4.0. Term UBERON:0002072, version 2026-06-19, retrieved 2026-08-24. Licence: CC-BY-4.0.

• Part of: integument and integumental system.
• A kind of: anatomical structure and organ component layer.
• contains: cutaneous vein, eyelid subcutaneous connective tissue, fascia of Camper, platysma, smooth muscle layer in fatty layer of subcutaneous tissue and subcutaneous adipose tissue, and 1 more.
• composed of: adipose tissue and loose connective tissue.
• Develops from: mesoderm.
• contributes to morphology of: subcutaneous adipose tissue.

Questions

Where is the hypodermis?

It sits within the integumentary system. Only the system is known. The position shown carries almost no spatial information.

What does the hypodermis connect to?

Part of: integument and integumental system.

Is the hypodermis the same in other species?

Leumas holds the same relationship vocabulary for every species it carries, so where another dataset records this structure you can put the two side by side on /compare.