endocardial cushion
The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves[GO]. Swellings of tissue present between the endocardial and myocardial cell layers that will give rise to the interstitial cells of the cardiac valves[ZFA]. Every claim on this page comes from the Leumas anatomy graph and carries its source.
What the endocardial cushion is
The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves[GO]. Swellings of tissue present between the endocardial and myocardial cell layers that will give rise to the interstitial cells of the cardiac valves[ZFA]. The atlas records it as a tissue at the tissue scale in the human body.
Where the endocardial cushion is
It sits in the thorax and trunk, within the cardiovascular system. Not positioned individually. Drawn inside the structure this dataset says contains it — the containment is asserted, the exact spot within it is not.
What the endocardial cushion connects to
The atlas records 14 typed relationships for it, across 4 kinds of connection. part of embryo, embryonic structure and endocardium, and 3 more.
Supply and innervation
This dataset asserts no arterial supply, venous drainage or innervation for the endocardial cushion. Only a minority of structures carry those edges here, so an empty answer means nothing has been recorded — not that there is nothing to record.
Also called
Also recorded as AV cushion, atrioventricular cushion, cardiac cushion, endocardial cushion tissue, atrioventricular canal cushion and endocardial cushions. Searching any of those names reaches this page.
Source
Uberon multi-species anatomy ontology (Mungall et al.), CC BY 4.0. Term UBERON:0002062, version 2026-06-19, retrieved 2026-08-24. Licence: CC-BY-4.0.
- Part of: embryo, embryonic structure, endocardium, heart, material anatomical entity and trunk.
- A kind of: embryonic structure, mesenchyme derived from neural crest and tissue.
- develops into: atrioventricular septum, atrioventricular valve, cardiac valve and sinoatrial valve.
- Develops from: neural crest.
Questions
Where is the endocardial cushion?
It sits in the thorax and trunk, within the cardiovascular system. Not positioned individually. Drawn inside the structure this dataset says contains it — the containment is asserted, the exact spot within it is not.
What does the endocardial cushion connect to?
Part of: embryo, embryonic structure, endocardium, heart, material anatomical entity and trunk.
Is the endocardial cushion the same in other species?
Leumas holds the same relationship vocabulary for every species it carries, so where another dataset records this structure you can put the two side by side on /compare.